abstract：:Nocturnal polygraphic recordings (electroencephalography, electro-oculography, submental and intercostal muscle electromyography, electrocardiography, respiration by thoracic strain gauges and oronasal thermistors) with continuous monitoring of arterial oxyhemoglobin saturation by pulse oximeter were performed in 8 pa...

journal_title：European neurology

authors： Manni R,Piccolo G,Banfi P,Cerveri I,Bruschi C,Zoia C,Tartara A

更新日期：1991-01-01 00:00:00

abstract：:The interpretation of the total phenytoin (PT) concentration can be problematic if valproic acid (VPA) is given as a comedication, because VPA displaces PT from the protein binding sites and can increase the free fraction of PT. In order to estimate the free or unbound PT concentration (PTf) from the total PT concentr...

journal_title：European neurology

authors： May TW,Rambeck B,Nothbaum N

更新日期：1991-01-01 00:00:00

abstract：:Kearns-Sayre syndrome has been associated with large heteroplasmic mitochondrial DNA deletions and morphological alterations at the cytological level. We have measured the activities of different respiratory chain complexes in 3 patients presenting mitochondrial DNA deletions and found no close correlation between gen...

journal_title：European neurology

authors： Reichmann H,Degoul F,Gold R,Meurers B,Ketelsen UP,Hartmann J,Marsac C,Lestienne P

更新日期：1991-01-01 00:00:00

abstract：:Stroke as a presenting manifestation of sarcoidosis has rarely been reported. This contrasts with the frequent anatomopathological findings of cerebrovascular involvement in neurosarcoidosis. We present a patient who developed acutely a right brachiofacial weakness and dysarthria. Pulmonary sarcoidosis was found. A br...

journal_title：European neurology

authors： Michotte A,Dequenne P,Jacobovitz D,Hildebrand J

更新日期：1991-01-01 00:00:00

abstract：:Tardive dyskinesia (TD) induced by antipsychotic drugs represents a great concern for patients and psychiatrists. Considering its pathophysiological mechanisms, there exists a convergence towards the development of postsynaptic dopaminergic hypersensitivity as a possible cause of TD. Hypersensitivity following recepto...

journal_title：European neurology

authors： Mouret J,Khomais M,Lemoine P,Sebert P

更新日期：1991-01-01 00:00:00

abstract：:Posterior tibial somatosensory evoked potentials were obtained in a group of cystic fibrosis patients and age-matched controls. A small but significant delay of the lumbar potential and larger delays of the early scalp potentials were observed. These findings are consistent with earlier pathological studies demonstrat...

journal_title：European neurology

authors： Staley K,Iragui VJ

更新日期：1991-01-01 00:00:00

abstract：:Thirty-three headache-free patients (19 F/14 M) suffering from common (n = 9) and classic migraine (n = 19) as well as cluster headache (n = 5) were investigated using the flow tracer 99mTc-hexamethyl propylenamino oxime and single photon emmission computed tomography. A regional decrease of cerebral tracer uptake was...

journal_title：European neurology

authors： Schlake HP,Böttger IG,Grotemeyer KH,Husstedt IW,Vollet B,Schober O,Brune GG

更新日期：1990-01-01 00:00:00

abstract：:To quantitate embolic risk we studied a retrospective series of 61 patients with strictly defined bacterial endocarditis. Eighteen patients had neurological complications attributable to cerebral embolism. Seventeen embolic episodes occurred prior to antibiotic treatment and 8 episodes after its commencement. The rate...

journal_title：European neurology

authors： Paschalis C,Pugsley W,John R,Harrison MJ

更新日期：1990-01-01 00:00:00

abstract：:Dopamine uptake sites, labelled by 3 nM [3H]GBR 12935, were reduced by 28-34% in post-mortem Parkinson's diseased striata (n = 22) compared to control striata (n = 28). There was no significant difference between post-mortem striata from schizophrenics (n = 16) and controls. Both dopamine D1 and D2 receptors are consi...

journal_title：European neurology

authors： Pearce RK,Seeman P,Jellinger K,Tourtellotte WW

更新日期：1990-01-01 00:00:00

abstract：:We report a patient with Down's syndrome (DS) who developed progressive parkinsonian symptomatology at the age of 43 years. His parkinsonism was responsive to levodopa/carbidopa, but he developed end of dose wearing off. We discuss basal ganglia and dopamine abnormalities in DS and suggest that DS may be associated wi...

journal_title：European neurology

authors： Singer C,Sanchez-Ramos J,Weiner WJ

更新日期：1990-01-01 00:00:00

abstract：:The binding of the dopamine uptake inhibitor [3H]GBR-12935 to postmortem putamen from a control group and patients with Alzheimer's disease/senile dementia of Alzheimer type (AD/SDAT) or vascular dementia (VD) was studied. The binding density (Bmax) in AD/SDAT was significantly reduced to 50% of control. A reduction o...

journal_title：European neurology

authors： Allard P,Alafuzoff I,Carlsson A,Eriksson K,Ericson E,Gottfries CG,Marcusson JO

更新日期：1990-01-01 00:00:00

abstract：:Within non-rapid eye movement sleep, two complementary modalities of arousal organization may be identified: (1) the cyclic alternating pattern (CAP), correlated with successive upward (phase A) and downward (phase B) fluctuations of arousal and arousal-related vegetative functions, and (2) non-CAP, corresponding to a...

journal_title：European neurology

authors： Terzano MG,Parrino L,Spaggiari MC

更新日期：1990-01-01 00:00:00

abstract：:A patient who on presentation fulfilled diagnostic criteria for benign intracranial hypertension subsequently developed a lymphocytic meningitis. A final diagnosis of neurosarcoidosis was made and the patient responded well to oral steroids. ...

journal_title：European neurology

authors： Redwood MD,Winer JB,Rossor M

更新日期：1990-01-01 00:00:00

abstract：:Fifteen chronic alcoholic male patients with impotence have been investigated with the electrophysiological method of sympathetic skin potentials recorded from the genital skin and with the electrically induced bulbocavernosus reflex. Both electrophysiological tests did not differ from those of normal controls. It was...

journal_title：European neurology

authors： Ertekin C,Almis S,Ertekin N

更新日期：1990-01-01 00:00:00

abstract：:Three patients with cerebral tumor involving diencephalic midline structures (2 malignant gliomas, 1 craniopharyngioma) and no metabolic abnormalities developed disorientation in time and place or coma with triphasic waves (TW) seen on electroencephalograms. Serial EEG recordings showed persistence or disappearance of...

journal_title：European neurology

authors： Aguglia U,Gambardella A,Oliveri RL,Lavano A,Camerlingo R,Quattrone A

更新日期：1990-01-01 00:00:00

abstract：:The pathogenesis of primary degenerative dementia is still unknown and current therapeutic approaches can aim only at ameliorating some of the symptoms associated with this brain disease. At present, most approaches, attempt to correct a cholinergic deficit. Although the therapeutic benefits obtained so far with curre...

journal_title：European neurology

authors： Markstein R

更新日期：1989-01-01 00:00:00

abstract：:In a direct (door-to-door) epidemiological study, the prevalence rate of cerebrovascular disease in the rural population of northwest Peloponnese, Greece, was found to be 995 strokes per 100,000 inhabitants over 20 years of age. This number is considerably lower than the prevalence rate (1,417 strokes per 100,000 inha...

journal_title：European neurology

authors： Paschalis C,Polychronopoulos P,Makris N,Kondakis X,Papapetropoulos T

更新日期：1989-01-01 00:00:00

abstract：:In a 14-year follow-up the improvement of language functions and the decrease of EEG abnormalities are described in a girl with the Landau-Kleffner syndrome. In this case, the results of subsequent EEG recordings do not permit conclusions about the course of the aphasia. Disappearance of focal spike and waves, bilater...

journal_title：European neurology

authors： van Dongen HR,Meulstee J,Blauw-van Mourik M,van Harskamp F

更新日期：1989-01-01 00:00:00

abstract：:A 28-year-old man with negative family history for neuromuscular diseases showed a distal myopathy. Creatine kinase was slightly increased. Two muscle biopsies were performed. The first showed myopathic features, rimmed vacuoles in a limited area and increase of free glycogen; the second showed only nonspecific pathol...

journal_title：European neurology

authors： Mongini T,Doriguzzi C,Palmucci L,Pollo B,Arnaudo E,Bresolin N

更新日期：1989-01-01 00:00:00

abstract：:Familial cases of HTLV-I-associated myelopathy (HAM) and adult T-cell leukemia (ATL), developing in a daughter and father, respectively, are reported. The coexistence of both diseases in a family has not been reported before. This supports the recent findings that ATL and HAM may be brought about by an identical virus...

journal_title：European neurology

authors： Shoji H,Kuwasaki N,Natori H,Kaji M,Miyamoto Y,Usuku K,Sonoda S,Osame M

更新日期：1989-01-01 00:00:00

abstract：:The central motor pathways were studied with the technique of percutaneous electrical stimulation of the central nervous system in 40 normal volunteers. There were no significant differences between the right and left sides, or between males and females. A linear correlation between the cortical latency (Lcor) or the ...

journal_title：European neurology

authors： Ugawa Y,Genba K,Shimpo T,Mannen T

更新日期：1989-01-01 00:00:00

abstract：:Positron emission tomography (PET) has opened new fields of investigation on clinicometabolic correlations in subcortical infarcts. Functional changes occurring in structurally unaffected brain regions represent one of the most interesting aspects of PET application. So far, the only one PET study on lacunar infarcts ...

journal_title：European neurology

authors： Di Piero V,Lenzi GL,Fieschi C

更新日期：1989-01-01 00:00:00

abstract：:A 16-year-old patient presenting with complex partial seizures occurring in the transition from a REM period to wakefulness is described. His baseline EEG showed generalized and symmetrical slow spike and wave complexes, on a normal background activity, activated by NREM sleep. Polygraphic and videotape recordings, ca...

journal_title：European neurology

authors： Silvestri R,De Domenico P,Musolino R,Mento G,Marabello L,Longo M,Di Perri R

更新日期：1989-01-01 00:00:00

abstract：:Five patients with monomelic spinal muscular atrophy are described. Clinical features included insidious onset of wasting and weakness of one limb, lack of involvement of the cranial nerves, brain stem, pyramidal tracts and sensory system, and a stable condition over a period of 4-20 years. Clinical findings, electrom...

journal_title：European neurology

authors： de Visser M,Ongerboer de Visser BW,Verbeeten B Jr

更新日期：1988-01-01 00:00:00

abstract：:40 patients with multiple sclerosis were investigated by magnetic resonance imaging (MRI) and computer tomography (CT). Additionally, cerebrospinal fluid (CSF) findings and evoked potentials (EPs; visual, brainstem) were evaluated. MRI findings were abnormal in 85% of the patients, whilst CT scan showed pathological c...

journal_title：European neurology

authors： Boné G,Ladurner G,Artmann W,Bsteh C

更新日期：1988-01-01 00:00:00

abstract：:A 39-year-old intravenous drug user presented with dysarthria and a syndrome of the left cerebellar hemisphere. While in hospital, he developed progressive brainstem findings. Repeated CT scans revealed a lucency in the white matter of the left cerebellar hemisphere. Brainstem auditory and short-latency somatosensory ...

journal_title：European neurology

authors： Lipton RB,Krupp L,Horoupian D,Hershkovitz S,Arezzo JC,Kurtzberg D

更新日期：1988-01-01 00:00:00

abstract：:Three patients with unusual presentations of basilar artery ectasia are described: subarachnoid hemorrhage was manifest in one and autonomic dysfunction developed in the other two. Aneurysmal rupture was the cause in the first patient, while compression of the brainstem and/or of the baroreceptor afferences of the IXt...

journal_title：European neurology

authors： Nogues M,Casas Parera I,Starkstein S,Micheli F

更新日期：1988-01-01 00:00:00

abstract：:In 128 patients with multiple sclerosis (MS) and 204 blood donors (control persons) the in vitro activation of 'Ficoll-purified' peripheral blood T lymphocytes was measured using the 3H-thymidine incorporation rate without (spontaneous proliferation) and with mitogen addition (concanavalin A, phytohemagglutinin). Mito...

journal_title：European neurology

authors： Trenn G,Kreuzfelder E,Hierholzer E,Scheiermann N,Bauer HJ,Bushart W

更新日期：1988-01-01 00:00:00

abstract：:Four patients who experienced isolated transient global amnesia had computed tomographic evidence for a cerebral infarct (3 cases) or hemorrhage (1 case). The medial part of the temporal lobe was involved in 2 patients (left in 1, right in 1), the left lentiform nucleus in 1 patient, and the left thalamus in 1 left-ha...

journal_title：European neurology

authors： Bogousslavsky J,Regli F

更新日期：1988-01-01 00:00:00

abstract：:In 167 patients with cerebrovascular disorders 323 carotid bifurcations were investigated by Duplex ultrasound. In 100 of these patients, additionally intravenous digital subtraction angiography (DSA) was performed and in 35 patients, also intra-arterial DSA was carried out. In 32 patients all three procedures were pe...

journal_title：European neurology

authors： Boné G,Ladurner G,Karas I,Grobovschek M,Punzengruber J

更新日期：1988-01-01 00:00:00

abstract：:A 20-year-old woman with Kearns-Sayre syndrome (KSS) suddenly experienced two episodes of diabetic coma. She was studied to determine whether diabetes mellitus (DM) resulted from insulin resistance or from an insulin secretion abnormality, using the euglycemic glucose clamp technique and the glucagon tolerance test. S...

journal_title：European neurology

authors： Tanabe Y,Miyamoto S,Kinoshita Y,Yamada K,Sasaki N,Makino E,Nakajima H

更新日期：1988-01-01 00:00:00

abstract：:Two prospective projects were started in May 1985 to evaluate the long-term effects of bromocriptine in patients with Parkinson's disease. One of the projects is to see if combination therapy with levodopa and bromocriptine is superior to levodopa alone with regard to the prevention of late side effects of levodopa th...

journal_title：European neurology

authors： Nakanishi T,Mizuno Y,Goto I,Iwata M,Kanazawa I,Kowa H,Mannen T,Nishitani H,Ogawa N,Takahashi A

更新日期：1988-01-01 00:00:00

abstract：:Estrogen receptor (ER) analysis was performed with an enzyme immunoassay using monoclonal antibodies against human ER protein (estrophilin) in 70 meningiomas. [3H]methyltrienolone, a synthetic androgen, was used for concurrent determination of the androgen receptor (AR)-binding activity. Low levels of ER immunoreactiv...

journal_title：European neurology

authors： Lesch KP,Schott W,Engl HG,Gross S

更新日期：1987-01-01 00:00:00

abstract：:MPTP, 1-methyl-4-phenyl-pyridinium ion (MPP+) and the structurally related compounds including N-methyltetrahydroisoquinilinium ion inhibited the tyrosine hydroxylase (TH) system in tissue slices of rat striatum at 10(-5) M. Mouse striatum is more susceptible to MPTP than rat striatum. A similar degree of inhibition b...

journal_title：European neurology

authors： Nagatsu T,Hirata Y

更新日期：1987-01-01 00:00:00

abstract：:A 32-year-old patient with a lifelong history of epileptic attacks is described. A skull X-ray showed a round calcified nonhomogenous left frontotemporal mass. A CT scan confirmed its presence, as well as displacement of the left lateral and the third ventricles. At surgery a calcified inactive hydatid cyst was totall...

journal_title：European neurology

authors： Micheli F,Lehkuniec E,Giannaula R,Caputi E,Paradiso G

更新日期：1987-01-01 00:00:00

abstract：:The present report evaluates the suppression of antiepileptic drugs in a group of 608 epileptics. Conditions for the suppression of antiepileptic treatment included a previous seizure-free period of 5 years under medication, and a careful evaluation of individual social and work-related circumstances. The reduction of...

journal_title：European neurology

authors： Oller-Daurella L,Oller L

更新日期：1987-01-01 00:00:00

abstract：:During the first 5 days after an intracranial haemorrhage, the red blood cells slowly haemolyse. Most of the oxyhaemoglobin, released in the cerebrospinal fluid, is transformed into bilirubin by an enzyme-dependent process. After 5 days, the haemolysis increases without a corresponding enhancement in the formation of ...

journal_title：European neurology

authors： Wahlgren NG,Lindquist C

更新日期：1987-01-01 00:00:00

abstract：:The authors themselves studied 26 patients. The EEGs were classified in terms of increasing severity in 5 categories. Incorporating over 400 cases from the literature, the authors correlated the initial EEG findings with the clinical outcome following cardiac arrest. Grade I EEG findings (normal alpha with theta-delta...

journal_title：European neurology

authors： Scollo-Lavizzari G,Bassetti C

更新日期：1987-01-01 00:00:00

abstract：:The report deals with the changes of brain functions in the course of traumatic apallic syndrome (TAS) by means of the EEG examination, in the classical way, and by computer analysis as well. The development of EEG changes during individual stages of the TAS is studied. The EEG examination was performed repeatedly in ...

journal_title：European neurology

authors： Strnad P,Strnadová V

更新日期：1987-01-01 00:00:00

abstract：:The therapeutic efficacy of Madopar HBS was investigated in 5 patients with advanced parkinsonism. They were under treatment with standard Madopar and suffered from marked fluctuations, mainly end-of-dose akinesia. All patients were abruptly switched from standard Madopar to the HBS formulation. For the first few days...

journal_title：European neurology

authors： Fischer PA,Baas H

更新日期：1987-01-01 00:00:00